Somatropin (Somatotropin) Benefits, Uses, Side Effects & Functions
Somatotropin—also known as human growth hormone (HGH) or simply as growth hormone (GH)—is a polypeptide produced by somatotrope cells in the pituitary gland. It supports skeletal growth in children and adolescents, and plays a role in metabolism, body composition, muscle growth and tissue repair in adults. In addition to the somatotropin naturally produced by the body, a synthetic form of HGH called somatropin is available with a doctor’s prescription. Certain health and bodybuilding supplements may also help increase somatotropin production through natural ingredients known as HGH releasers.
Functions of Somatotropin
Children and adolescents require somatotropin for proper growth and development; those with an HGH deficiency may require somatropin injections to achieve normal height. In adults, somatotropin helps maintain healthy tissues and organs. It can also increase bone density, muscle mass, and protein synthesis as well as decrease body fat and improve exercise capacity. Because HGH production naturally declines with age, some adults take somatotropin-boosting supplements to enhance their athletic performance and combat the physical signs of aging.
Sources of Somatotropin/Somatropin
For most individuals, the primary source of somatotropin is the body’s endogenous production by the somatotropic cells of the pituitary gland. The body produces its highest levels of somatotropin during childhood and adolescence; these levels significantly decline when the individual reaches full adult height. Scientists have also developed a synthetic form of somatotropin known as somatropin or somatrem, using E. coli or mammalian cells to create therapeutic proteins in a laboratory setting. Somatropin is chemically identical to the somatotropin that is produced by the pituitary gland and administered by subcutaneous injection. It is a regulated substance, which means it can only be legally prescribed for FDA-approved uses.
Since somatropin injections are not legally available to healthy adults, those seeking the benefits of somatotropin may opt to take natural supplements that are designed to boost the body’s own HGH production. Certain amino acids are recognized as natural HGH releasers—including GABA, arginine, ornithine, glutamine, lysine, tyrosine and glycine—so dietary supplements containing these ingredients may help increase somatotropin levels.
Somatropin Benefits and Uses
The pituitary gland’s secretion of somatotropin supports bodily growth and development throughout childhood and adolescence, so the most common reason for prescribing somatropin is to treat children and teens with HGH deficiency or specific medical conditions. FDA-approved pediatric uses of somatropin include idiopathic growth hormone deficiency, Noonan syndrome, Turner syndrome, Prader-Willi syndrome, chronic renal insufficiency, short stature homeobox-containing gene (SHOX) deficiency, and idiopathic short stature.
Although HGH levels naturally decline with age, somatotropin continues to play a role throughout adulthood—helping to regulate metabolism and protein synthesis and promoting organ, tissue and bone health. Somatropin may be legally prescribed to adults who have severe HGH deficiency, which normally occurs due to a pituitary adenoma (tumor) or adenoma-related surgery or radiation treatments. It is also sometimes prescribed to prevent or minimize wasting in AIDS patients.
Somatropin injections can improve bone density, muscle mass and exercise capacity in adults with HGH deficiency, and they can produce similar outcomes in healthy adults. As a result, some bodybuilders and athletes take somatropin to enhance their athletic performance and physique. However, it should be noted that somatropin cannot legally be prescribed for such purposes. Furthermore, the World Anti-Doping Agency (WADA), International Olympic Committee and numerous sports organizations have banned the use of HGH injections among athletes.
Given the potential repercussions associated with illegal somatropin injections, many bodybuilders, athletes and aging adults have starting taking natural HGH supplements to help the body increase its own somatotropin production. Proponents of somatotropin-boosting supplements report that these natural HGH releasers have helped them develop lean muscle, improve their strength and endurance, and recover from intense workouts and injuries more quickly. They also credit HGH supplements with enhancing their body composition and slowing the visible signs of aging.
Somatropin Side Effects
Individuals considering HGH injections should be aware of somatropin side effects and interactions. Some users have experienced an allergic reaction, with symptoms such as itching or rashes, chest pain, difficulty breathing, or swelling of the face, tongue, or throat. Other possible side effects include headaches, nausea, vomiting, blurred vision, fluid retention, swelling of the hands or feet, muscle stiffness or pain, and burning, tingling or numbness in the skin. Somatropin may increase the risk of developing diabetes, cancer or pancreatitis, and it can cause dislocation of the hipbone that results in limping or knee/hip pain. Interactions have been recorded when somatropin is used with estrogen hormone replacement or glucocorticoids (such as prednisone or hydrocortisone), and somatropin can cause adverse effects in patients with diabetes, scoliosis, kidney disease and certain other medical conditions.
Somatotropin-boosting HGH supplements tend to have fewer and less severe side effects than somatropin injections; however, the side effects and interactions will vary depending on the supplement’s ingredients.
More detailed safety information on somatropin side effects, interactions and precautions can be found on the Mayo Clinic website. For natural somatotropin-boosting supplements, refer to the relevant ingredient articles on HGH.com to learn about potential side effects and interactions. As with any medication or health supplement, it is best to consult your physician before using somatropin injections or natural HGH supplements.
Natural Somatotropin/HGH Releasers
Many of the health and bodybuilding supplements available around on the market (online or offline) that are formulated to naturally increase somatotropin/HGH levels. Only fews of these HGH releaser that really work. Each supplement has the purpose of increasing your HGH Levels naturally through HGH supplementation. Each product is different, has different ingredients, and is meant to accomplish the same goal. Everyone is different and certain people respond better to certain formulas than others.
Below best proven HGH supplements that actually work for bodybuilding, weight loss, anti-aging and height.
Somatropinne HGH – This natural Somatropinne HGH capsules contain a proprietary blend of L-arginine, cowhage, maca and horny goat weed. As an over-the-counter somatotropin releaser, this supplement is formulated to help athletes gain lean muscle and increased energy while also providing weight-loss and anti-aging benefits.
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HGH-X2 Somatropinne – HGH-X2 Somatroppine is an HGH releaser. It’s formulated to trigger your body’s pituitary gland into releasing more HGH into your bloodstream. Expect quality, lean muscle gains, quick fat loss and faster recovery times.
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HGH 30,000 Nanograms Spray –30,000 Nanogram HGH Spray are designed to promote somatotropin production, muscle growth, increased energy and other health benefits. They contain a powerful combination of amino acids as well as other natural ingredients such as colostrum, GABA, cowhage (mucuna pruriens), long jack and deer antler velvet.
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Growth Factor Plus – As its name suggests, Growth Factor Plus is intended to support height growth as well as bone and joint health. Its proprietary blend of ingredients features amino acids such as L-arginine, L-ornithine, L-lysine, L-glycine, L-glutamine, and L-tyrosine.
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